Bogoslovskaya O.A., Sizova E.A., Polyakova V.S., Miroshnikova S.A., Leipunsky I.O., Olkhovskaya I.P., Glushchenko N.N.
STUDYING OF SAFETY OF COPPER NANOPARTICLES INTRODUCTION WITH DIFFERENT PHYSICAL-CHEMICAL CHARACTERISTICS INTO ANIMALS’ ORGANISM ^{[№ 2 ' 2009]}
The appraisal of safety of metals nanoparticles introduction into animals’ organism was conducted at indexes of toxicity (MPD – maximal tolerable dose, LD₅₀, LD₁₀₀) of copper nanoparticles, which are different at size and content of crystalline copper in nucleus of particles. It is established that particles with size 33,8 ± 0,3 nm have more toxicity in comparison with nanoparticles with size 103,0 ± 2,0 nm. The toxicity of modified copper nanoparticles is in 2.5 – 6 times less then toxicity of copper salts.