Fomina M.V., Mikhailova E.A., Zherebyateva O.O., Kirgizova S.B., Lyashenko I.E., Sokolova O.Ya.
VALUABLE ORIENTATIONS OF FOREIGN STUDENTS UNDER SOCIAL INTERACTION UNDER THE CONDITIONS OF THE UNIVERSITY EDUCATIONAL ENVIRONMENT ^{[№ 2 ' 2020]}
Russian universities are actively positioning themselves on the international export market of educational services, and therefore educational migration has become the realities of our day. Significant is the formation of the value orientations of foreign students in the aspect of social interaction in the educational environment of the university.
We conducted a study on the diagnosis of value orientations of foreign students of a medical university according to the method of S. Schwartz. The statistics of answers showed that the most significant for students in this period of life are the achievements associated with educational success (80.8 % of respondents). According to the data obtained, being in a foreign country, foreign respondents in 82.2 % of cases put priority on the well-being of people close to them. In turn, 78.1 % of foreign respondents noted for them the importance of independence and freedom that they received when they came to study in Russia. As the study showed, power and tradition are not a priority for entering the educational environment of the university for respondents (among 80.8 %). At the same time, 76.7 % of Indian students do not prioritize manifestations of social power, such as controlling other people and managing their actions. With regard to material security, 60.9 % of respondents prefer to think more about the soul than about the material, which may be explained by differences in incomes of families of students. Response statistics showed that 72.0 % of young people rate safety as not very important, which indicates a comfortable stay in Russia.
Thus, the educational environment in the context of the higher education system is decisive in the formation of personal values and the disclosure of the internal potential of foreign students, thereby significantly determining the image, prestige and relevance of the university.

Fomina M.V., Mikhaylova E.A., Aznabaeva L.M., Kirgizova S.B., Zherebyateva О.О.
THE COMMUNICATIVE COMPONENT OF EDUCATIONAL CONTENT IN THE ASPECT OF CORPORATE CULTURE MEDICAL UNIVERSITY ^{[№ 6 ' 2018]}
Professional medical activity has a number of specific features, its success is determined not only by professional knowledge and skills, but also interpersonal communication skills. In connection with the increasing requirements to the level of communicative competence of a specialist, the formation of a communicative component of the content of education that contributes to the formation of professionally significant qualities in students of a medical University, providing a communicative basis for future successful professional activity becomes relevant.
We carried out a study on the diagnosis of the empathic ability of medical students on techniques A. Mehrabian, N. Epstein and V.V. Boyko. The study showed that 39.4% of the surveyed students have an average level of formation of empathic abilities, 51.1% — low and 9.5% — very low. In 89.6% of girls in communication dominated emotional channel, due to the greater ability of girls to enter into an emotional resonance with others. 54.5% of the boys showed the rational and 44.4% — intuitive channels of empathy. Attention is drawn to the fact that only 34.4% of students demonstrated an average ability to empathy, which indicated a lack of skills to create an atmosphere of information and energy exchange in interaction with patients, and 55.5% of respondents did not identify themselves as a subject of empathic relations in future professional activities.
Our results indicate the need for early diagnosis and further development of professionally significant communicative qualities of the future doctor at all stages of Higher education, based on the principles of corporate culture of the medical University and the traditions of the Russian medical school.

Fomina M.V., Mikhailova E.A., Kuznetsova N.P., Morozovа A.I., Kirgizova S.B., Aznabaeva L.M., Zherebyatyeva O.О., Safarova D.R.
MEDICAL-ECOLOGICAL ASPECTS OF RESISTANCE MICROFLORA IN CHILDREN WITH ACUTE INFLAMMATORY DISEASES OF THE UPPER RESPIRATORY TRACT ^{[№ 12 ' 2017]}
Inflammatory diseases of the upper respiratory tract bacterial nature of the disease, which most often otolaryngologists in modern conditions are becoming increasingly epidemiological, economic and social significance. The trend in recent years has been the changing epidemiology of causative agents of this disease, the properties of the pathogens, resistance to drugs. Along with this, there are regional differences of indicators of resistance of microorganisms, which complicates the selection of antimicrobial agents in starting empirical therapy of acute rhinosinusitis in children. A monitoring study of the species composition of microflora of nasal cavity showed that, along with the leading (80.3 %) etiologically significant representatives of pathogenic flora — gram-positive cocci (mainly Staphylococcus аureus and Staphylococcus haemolyticus), the microflora was represented by gram-negative rods bacteria of the genus Klebsiella (Klebsiella pneumonicae) — 1.6 %. Among non-fermenting gram-negative bacteria in 0.8 % of cases were allocated to members of the genus Pseudomonas. According to the study, the selected isolates of Staphylococcus haemolyticus were not sensitive to ampicillin/sulbactam in 75 % of cases, ceftazidime — 73.3 %, the highest activity possessed antimicrobial agents ceftriaxone (87.5 %) and azithromycin (89.1 % of cases). In turn, Staphylococcus аureus in 54.5 % of cases were sensitive to ceftazidime, 45.4 % to oxacillin. Observed high sensitivity of the pathogen to erythromycin (100 %), gentamycin (100 %), ofloxacin and ceftriaxone — 90.9 % of cases. The results obtained, taking into account regional differences in the indicators of resistance of microorganisms and their sensitivity to antibiotics, can be used in starting the empirical therapy of acute rhinosinusitis in children.

Makhalova G.O., Mikhailova E.A., Kshnyaseva S.K., Konstantinova O.D., Zherebyatyeva O.O., Fomina M.V., Pervushina L.A., Aznabaeva L.M., Kirgizova S.B., Lyashenko I.E.
HYPOBARIC HYPOXYTHERAPY AS THE FACTOR OF THE REGULATION OF MICROECOLOGICAL VIOLATIONS OF THE UROGENITAL BIOTOPE AT NONCARRYING OF PREGNANCY PREGNANCY NOT INCUBATION ^{[№ 8 ' 2017]}
In the clinical medicine, various methods of the hypoxic system are widely used as a non-medicament means of correction of the functional state. The study included the biological material of 90 women planning a pregnancy. The authors evaluated the effect of hypobaric hypoxic therapy in complex pregravid preparation for the normalization of cytokine levels in the cervical discharge in women with habitual miscarriages of the fetus. Concentrations of IL-1β and γ-IFN were performed using the solid-phase ELISA method, using reagent kits from Cytokine (St. Petersburg, Russia). Hypobaric treatment is carried out in the Russian medical vacuum unit-the Ural-1 pressure chamber. In women, before the planned pregnancy, the level of IL-1β averaged (40.7 ± 2.8) pg/ml, the concentration of INF-γ was (46.0 ± 2.3) pg/ml. Comparative evaluation with healthy indices revealed that these values exceed the lessons of the test markers in healthy women. In patients treated under the conditions of a pressure chamber, indications, in comparison with the initial, the content of proinflammatory cytokines, namely IL-1β, was determined on average in a concentration of (17.9 ± 2.8) pg/ml. As for changes in the concentration of INF-γ, its level significantly decreased after hypobarotherapy and amounted to (6.1 ± 1.3) pg/ml. Based on the results of the work, the authors worked out a method for hypobaric hypoxic therapy, suitable for treating this group of patients. The essence of the technique is that the inclusion in the complex pregravid preparation of 22 GPG sessions for 2 hours daily may be expedient, since it leads to a level of proinflammatory cytokine levels, bringing them closer to the level of healthy women.

Mikhaylova E.A., Fomina M.V., Kirgizova S.B.
MICROBIC ECOLOGY OF PALATINE TONZILSAT PATIENTS WITH CHRONIC TONSILLITIS ^{[№ 10 ' 2015]}
Despite some progress in treatment, chronic tonsillitis (CT) takes a leading place in the structure of ENT morbidity and is considered, according to the International classification of diseases and health-related (MCB), as the disease associated with bacteria of the species Streptococcus pyogenes. Other microorganisms — Staphylococcus aureus, Haemophilusinfluensae, β-haemolytic streptococci of group A, more rarely Streptococcus groups C and G, are actively producing β-lactamases are consideredcopathogen — microorganisms colonizing the upper respiratory tract, but do not play a predominant etiologic role in the development of inflammation. A controversial opinion in the scientific world regarding the etiology of the disease is associated with regional characteristics of microorganisms and methods of sampling and research methods. The level of microbial contamination of the elements lymphadenoid pharyngeal ring is often underestimated. The disease often takes a chronic, protracted course, there is the risk of life-threatening complications. In this regard, a particular problem of conservative treatment of chronic tonsillitis is the identification of pathogenic microorganisms, localized in the tonsils with subsequent elimination of the pathogen. The paper presents the results of the study the qualitative and quantitative composition of microflora in the mucosal surface of the tonsils in patients with chronic tonsillitis before and after treatment with drugs traditional treatment Protocol. The comparison of the results of the level of microbial contamination of habitat.

Fomina M.V., Kirgizova S.B., Aznabaeva L.M., Mikhailova E.A.
NEW OPPORTUNITIES DRUGS USED IN TREATMENT OF BACTERIAL INFECTIONS, FOR THE PREVENTION OF BACTERIA CARRIER ^{[№ 10 ' 2015]}
Sanation / preventive measures of carrier state from the body — one of the problems of modern medicine. Search for fundamentally new approaches, which should include an environmentally sound and individualized methods needed to improve the rehabilitation / prevention of bacteria. The possibility of using biologically active substances (endogenous interferon inducers and antibiotics) used in therapy for the prevention of bacterial infections Staphylococcus aureus carriers on the mucosa of the upper respiratory tract was investigated. Anticarnosine sign of staphylococci that in the differential diagnosis of transient resident of bacteria, was the most highly informative and the ability of bacteria to biofilm formation, is caused by infection and long-term persistence of the pathogen in the body used to work as a biological targets. It was found that the most significant reduction in anticarnosine feature of the original value recorded under the influence of substances of synthetic origin. The highest result of inhibiting drugs accounted for interferon inducers of class acridone — Neovir (71.2 ± 10.0 % ↓) and Cicloferon (74.6 ± 7.9% ↓). Chosen concentration and studied the action subinhibitory concentrations of antibiotics ampicillin and ceftriaxone. It was revealed that in subbacteriostatic concentrations, they have the same in direction but at different severity of effect on the ability of bacteria to form a biofilm. Both drugs inhibit the ability of bacteria to form a biofilm, thus more effective was ceftriaxone (67.7 ± 3.5% ↓) compared with ampicillin (55.1 ± 3.9% ↓). The data on the nature of the impact of drugs on the persistent characteristics of staphylococci can be used for the selection of promising new drugs for preventive measures of Staphylococcus aureus bacteria carriers.

Bukharin O.V., Kirgizova S.B., Kartashova O.L., Potekhina L.P.
ANTICARNOSINE ACTIVITY AND ITS ROLE AT MICROORGANISMS’ PERSISTENCE ^{[№ 12 ' 2006]}
Evidences of anticarnosine activity (ACrA) of bacteria at their persistence are got on the model of experimental staphylococcus infection. The analysis of feature’s prevalence and intensity of clinical bacteria isolate showed that staphylococcus had ACrA predominantly; at the same time the high meanings of the feature were registered at cultures, distinguished from biotope with high concentration of carnosine (olfactory epithelium of mucous tunic of nasal meatus) which had meaning at phenomenon of bacteria carrying of these microorganisms.

^{[№ 5 (app.1) ' 2006]}

Kartashova O.L., Kirgizova S.B., Bala S.S.
BIOLOGICAL CHARACTERISTICS OF MICROFLORA, EVOLVED FROM MILK AND OPPORTUNITY OF ITS USE IN FORECASTING OF COW’S MASTITIS DEVELOPMENT ^{[№ 5 (app.1) ' 2005]}
Microflora, evolved from milk of health and ill animals was studied in this article. The forecasting models of development of cow’s mastitis of streptococcic and staphylococcic ethiology were created on the base of obtained data of prevalence and intensity complex of microorganisms biological characteristics.