Bikmetova E.R., Menshikova I.A., Ramazanova L.M., Ivanova G.V., Kamilov F.Kh.
EFFECTIVENESS OF ACTIVITY OF ANTIOXIDANT VITAMINOUS PREPARATION ON METABOLISM OF BONE TISSUE AT CHRONIC INTOXICATION BY THE DICHLOROETHANE DURING THE EXPERIMENT ^{[№ 12 ' 2010]}
Chronic (during two months) dayly intoxication by the dichloroethane in the cumulative doze of 0,1 LD50 of mature white rats causes strengthening the processes of free-radical oxidation, reduction in the activity of the ferments of antioxidant protection and increase in the content of free hydroxiprolin in homogenates of the epiphyses of tubular bones. In the plasma of the blood of experimental animals the level S-bodypeptids of a collagen of the type I repeatedly increases with the constant activity of bone alkaline phosphatase. The treatment of animals by vitamin preparation "Triovit" during three weeks at the dose of 50 mg/kg in a 24 hour period against the background to intoxication by dichloroethane renders positive therapeutic effect on the exchange of the bone, reducing the intensity of chemiluminescence, the accumulation of the primary and secondary products of lipoperoxidation, strengthening the activity of fermentation antioxidants, suppressing resorptive processes.

Bikmetov E.Yu.
THE PROBLEM OF UNITY OF SOCIAL EDUCATIONAL SUBJECTS: GENETIC ASPECT ^{[№ 7 ' 2003]}
The article is devoted to research of methodological principals of secondary education, and also to the analysis of subject problem of educational activity. The author, tracing the evolution of such subjects of educational process as personality, family and school, accents his attention on their unity. The educational systems are regarded as open systems, which are dynamically interconnected with social-cultural and social-economical conditions.