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2012, № 6 (142)



Sheina N.I. BIOSAFETY EVALUATION CRITERIA OF MICROORGANISMS USED IN THE BIOTECHNOLOGY INDUSTRYBiosafety assessment based on the study of microbial pathogenicity and adverse action of 29 biotech strains was conducted. The dependence of the intensity immunotropic, and dysbiotic sensitive effects of the taxonomic position of microorganisms has been found. Sanitary classification of microorganisms in the degree of hazard effects was proposed and unified with the recommendations of international organizations.Key words: biosafety, microorganisms, pathogenicity, regulation.

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References:

1. Brewers Y.P., Myalina L.I., Korolik V.V. The evaluation criteria of the pathogenic properties of producer strains proposed for use in industrial microbiological synthesis. Guidelines. — M., 1992. — 20 р.

2. Staging studies to substantiate the maximum permissible concentrations of industrial strains of microorganisms and on the basis of finished dosage forms in the working area. Guidance. — Moscow, USSR Ministry of Health. — 1983. — № 2955-83. — 16 p.

3. Rakhmanin J.A., Bagdasarian G.A., Nemyria V.I., Sergeyuk N.P. Basic approaches to the valuation of biological contamination // Hygiene and Sanitation. — 2001. — №1. — P. 12–15.

4. Sergeyuk, N.P. Scientific basis for risk assessments and hygienic industrial microorganisms: Diss. MD. — M., 2004. — 240 р.

5. Scriabin E.G., Sheina N.I. Experimental assessment immunotropic activity of industrial microorganisms // Russian J. of Immunology. — 2004. — V. 9. — suppl. Combined immunological forum. — P. 123.

6. Shein, N.I. Hygienic aspects of studying the nature of the biological action of industrial microorganisms // Materials IY Russian Congress "Occupation and Health". — Moscow, October 25–27, 2005. — P. 164–165.

7. Sheina, N.I. Toxicological and hygienic evaluation of biotech microbial strains // Bulletin of the Russian State Medical University. — 2007. — №3 (56). — P. 66–71.

8. Sheinа, N.I. Criteria imbalance in intestinal micro-ecology of the system hygienic standards and risk assessment of industrial microorganisms // Occupational Medicine and Industrial Ecology. — 2007. — №11. — P. 21–26.

9. Sheinа N.I., Budanov E.V. Rating microecological intestinal imbalance with exposure to industrial microorganisms in toxicological studies hygienic // Poison Journal. — 2005. — №5. — Р. 23–27.

10. Sheinа N.I., Scriabin E.G., Ivanov N.G. Comparative characteristics of immunotropic activity of microorganisms in industrial hygienic standards // Poison Journal. — 2005. — №3. — P. 12–15.


About this article

Author: Sheina N.I.

Year: 2012


Editor-in-chief
Sergey Aleksandrovich
MIROSHNIKOV

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