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Glushchenko N.N.
Miroshnikova E.P., Arinzhanov A.E., Glushchenko N.N., Vasilevskaya S.P. EXCHANGE OF CHEMICAL ELEMENTS IN ORGANISM OF THE USE OF CARP NANOPARTICLES OF COBALT AND IRON IN THE DIET Studies to assess the impact of iron and cobalt in different chemical form (mineral salts, metal nanoparticles) on the exchange of chemical elements in carp revealed significant changes in the concentrations in the body of the fish calcium, phosphorus, iron, cobalt, iodine, etc. Key words: minerals, fish feeding, nanoparticles.
Sizova E.A., Miroshnikov S.A., Lebedev S.V., Glushchenko N.N. EFFECT OF MULTIPLE DOSES OF NANOPARTICLES COPPER ON THE ELEMENTAL COMPOSITION OF RAT LIVER The results of studies on the effect of copper nanoparticles on the mineral composition of the liver with varying degrees of stress the body. Is set change the microelement status of the liver and increase the ratio of trace elements in the direction of the elements that have influence gen damaging. Key words: copper nanoparticles, liver, mineral composition.
Sizova E.A., Lebedev S.V., Polyakova V.S., Glushchenko N.N. STRUCTURAL AND FUNCTIONAL REORGANIZATION OF THE RAT SPLEEN IN INTRAMUSCULAR INJECTION OF CU 10X COPPER NANOPARTICLES By using immuno-histochemical method we revealed features of structural and functional reorganization of the rat spleen in single and multiple intramuscular injection of copper nanoparticles. Key words: spleen, nanoparticles, immunohistochemistry.
Bogoslovskaya O.A., Sizova E.A., Polyakova V.S., Miroshnikova S.A., Leipunsky I.O., Olkhovskaya I.P., Glushchenko N.N. STUDYING OF SAFETY OF COPPER NANOPARTICLES INTRODUCTION WITH DIFFERENT PHYSICAL-CHEMICAL CHARACTERISTICS INTO ANIMALS’ ORGANISM The appraisal of safety of metals nanoparticles introduction into animals’ organism was conducted at indexes of toxicity (MPD – maximal tolerable dose, LD50, LD100) of copper nanoparticles, which are different at size and content of crystalline copper in nucleus of particles. It is established that particles with size 33,8 ± 0,3 nm have more toxicity in comparison with nanoparticles with size 103,0 ± 2,0 nm. The toxicity of modified copper nanoparticles is in 2.5 – 6 times less then toxicity of copper salts.
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Editor-in-chief |
Sergey Aleksandrovich MIROSHNIKOV |
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