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Medvedev I.N.

2007, № 12


Medvedev I.N., Goryainova I.N., Belova T.A.
POSSIBILITIES OF PHARMACOLOGICAL CORRECTION OF THROMBOCYTE DYSFUNCTION OF NEWBORN CALVES WITH DYSPEPSIA
Increase of aggregative function of thrombocytes in vitro and in vivo is revealed at newborn calves with dyspepsia. In the base of these abnormalities, abnormalities of cholesterol and phospholipids correlation in thrombocyte membranes, increase of middle molecules level content in plasma and blood platelets, activation of lipids peroxidation in them, synthesis strengthening in vascular wall of Villebrand factor and increase of thromboxaneformations level in blood platelets are laid. Thrombocytes activation is a leading reason of blood coagulation increase of newborn calves with dyspepsia. Correction of abnormalities of thrombocyte link of hemostasis is possible with help of pathogeneticly substantiated complex from phosphopag, ecos and calcium gluconate, able to decrease middle molecules level in an organism and to correct lipids peroxidation.


Editor-in-chief
Sergey Aleksandrovich
MIROSHNIKOV

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© Электронное периодическое издание: ВЕСТНИК ОГУ on-line (VESTNIK OSU on-line), ISSN on-line 1814-6465
Зарегистрировано в Федеральной службе по надзору в сфере связи, информационных технологий и массовых коммуникаций
Свидетельство о регистрации СМИ: Эл № ФС77-37678 от 29 сентября 2009 г.
Учредитель: Оренбургский государственный университет (ОГУ)
Главный редактор: С.А. Мирошников
Адрес редакции: 460018, г. Оренбург, проспект Победы, д. 13, к. 2335
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